ceesdekker.net - An Overview
ceesdekker.net - An Overview
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‘Indeed, that's about suitable. I look for a Bodily understanding of biological units within a base-up way. I believe you could possibly distinguish three traces of investigate in my group at this time. The very first problems chromosome structure: How will you receive a metre-lengthy DNA polymer folded and organised in this type of microscopic mobile? Now we have created visualisation tactics that allow for us to review how, one example is, SMC proteins loop DNA (online video on Youtube) to be able to Create up chromosomes.
1996, very first mesoscopic cost density waves devices; and very first electrical measurements on only one metal nanocluster amongst nanoelectrodes
Dynamics of initiation, termination and reinitiation of DNA translocation from the motor protein EcoR124I
Our function was speedily adopted up by Some others, most notably by Phaedon Avouris and colleagues at IBM, who in Oct 1998 released their conclusions on transistors comprised of one- and multi-walled carbon nanotubes in Used Physics Letters.
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Cornelis (Cees) Dekker (Haren, seven april 1959) is een Nederlandse natuurkundige en universiteitshoogleraar verbonden aan de Technische Universiteit Delft. Van 2010 tot en fulfilled 2018 was hij tevens directeur van het Kavli Institute of Nanoscience in Delft. Zijn vakgebied is de moleculaire biofysica; hierbij beweegt hij zich op het grensvlak van de https://www.ceesdekker.net natuurkunde en de biologie waarbij hij gebruikmaakt van de zogeheten nanotechnologie, de technieken om aan enkele atomen en moleculen te kunnen meten.
We use nanofabricated microfluidic structures to pattern spatial boundaries for microorganisms and biomimetic vesicles with reconstituted protein networks which assess the fundamental function of spatial confinement on the molecular and cellular level. Our projects include the following:
Dynamic ParB–DNA interactions initiate and sustain a partition condensate for bacterial chromosome segregation
In 1993, to be a young and eager associate professor at Delft College of Technology, I had originally concentrated the analysis efforts of my team on measuring the electrical conductance of only one conducting-polymer molecule. Inside two several years, we experienced created a device during which one wire of the phthalocyaninepolysiloxane polymer was related between two intently spaced metallic nanoelectrodes.
But carbon nanotubes have remained a study subject of appreciable interest to several. In fact, the outlook on using carbon nanotubes to create practical equipment, in spots including radio-frequency electronics, electronic electronics and versatile electronics, stays vivid.
Case in point (four) of bending configurations in 3D simulations of DNA rods on nanopores. A part of the membrane is demonstrated in grey, the rim of your pore is highlighted in purple, in addition to a 3D rendering on the movement from the DNA rod is displayed.
2001, discovery of one-electron transistors at area temperature determined by nanotubes; realization of initial logic circuits with carbon nanotube products; and discovery of your molecular construction of DNA repair service enzymes with AFM
Developments in nanotechnology in the 1990s manufactured setting up electronic devices from single molecules a possibility. Cees Dekker recounts how his group developed a place-temperature transistor based on just one carbon nanotube.
2004, discovery of latest physics in translocation of DNA through nanopores; initially experimental examine of ions conduction in nanofluidic channels; 1st electrochemistry with personal one-wall carbon nanotubes; STM detection and Charge of phonons in carbon nanotubes; initial electrical docking of microtubules on kinesin-coated nanostructures; to start with biophysics characterization on the mechanical Qualities of double-stranded RNA; and to start with solitary-molecule analyze of DNA translocation by a restriction-modification enzyme.